Found 12 matching trials
A Dose Escalation Study of Gefapixant (AF-219/MK-7264) in Refractory Chronic Cough (MK-7264-010)
PHASE2A randomized, double-blind, placebo-controlled, crossover, dose escalation ...
Location
Multiple Locations
The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)
PHASE2The purpose of this study is to assess the efficacy of gefapixant (AF-219/M...
Location
Afferent Investigative Site
The Pharmacokinetics of Gefapixant (MK-7264) in Participants With Renal Insufficiency (MK-7264-026)
PHASE1This trial aims to evaluate the plasma pharmacokinetics of gefapixant (MK-7...
Location
Clinical Pharmacology of Miami ( Site 0001)
A Study to Evaluate the Effect of Gefapixant (AF-219/MK-7264) on Methacholine Hyper-reactivity in Participants With Asthma (MK-7264-009)
PHASE2This is a randomized, double-blind, double-dummy, placebo-controlled, three...
Location
Multiple Locations
A Study to Assess the Tolerability of a Single Dose of Gefapixant (AF-219/MK-7264) in Subjects With Idiopathic Pulmonary Fibrosis (IPF)
PHASE2This study assesses the tolerability of a single dose of gefapixant (AF-219...
Location
American Health Research
Effect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (MK-7264-014)
PHASE2The primary objective of this study was to assess the effect of a single do...
Location
Multiple Locations
An 8-Week Refractory Chronic Cough Study (MK-7264-021)
PHASE2This was an 8-week randomized, parallel, double-blind, placebo-controlled s...
Location
Afferent Investigative Site
A Multiple-Dose Pharmacokinetics Study of Two Gefapixant (AF-219/MK-7264) Formulations
PHASE1The purpose of this study is to compare the multiple dose pharmacokinetics ...
A 12-Week Study in Participants With Refractory Chronic Cough (MK-7264-012)
PHASE2This study is designed to evaluate the efficacy of three dose regimens of g...
Location
Multiple Locations
Effect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity (MK-7264-015)
PHASE2The primary objective of this double-blind crossover study is to assess the...
Location
The Medicines Evaluation Unit